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	<id>https://boincsynergy.ca/wiki/index.php?action=history&amp;feed=atom&amp;title=The_Lattice_Project</id>
	<title>The Lattice Project - Revision history</title>
	<link rel="self" type="application/atom+xml" href="https://boincsynergy.ca/wiki/index.php?action=history&amp;feed=atom&amp;title=The_Lattice_Project"/>
	<link rel="alternate" type="text/html" href="https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;action=history"/>
	<updated>2026-07-16T07:09:24Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1715&amp;oldid=prev</id>
		<title>Al Piskun at 21:01, 14 July 2026</title>
		<link rel="alternate" type="text/html" href="https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1715&amp;oldid=prev"/>
		<updated>2026-07-14T21:01:41Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 21:01, 14 July 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l37&quot;&gt;Line 37:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 37:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[File:University of Maryland (5354729497).jpg|thumb|The Lattice Project was developed and administered at the [[wikipedia:University of Maryland, College Park|University of Maryland, College Park]].]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[File:University of Maryland (5354729497).jpg|thumb|The Lattice Project was developed and administered at the [[wikipedia:University of Maryland, College Park|University of Maryland, College Park]].]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&#039;&#039;&#039;The Lattice Project&#039;&#039;&#039; was a discontinued grid computing and [[wikipedia:volunteer computing|volunteer computing]] system operated by the Laboratory of Molecular Evolution at the [[wikipedia:University of Maryland, College Park|University of Maryland]], College Park.&amp;lt;ref name=&quot;wikipedia&quot;&amp;gt;{{Cite web |title=The Lattice Project |url=https://en.wikipedia.org/wiki/The_Lattice_Project |work=Wikipedia |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Rather than being a single program, Lattice combined several distinct computing resources, including dedicated [[wikipedia:HTCondor|Condor]] pools, [[wikipedia:Portable Batch System|PBS]] compute clusters, and a public [[wikipedia:BOINC|BOINC]] volunteer pool, into one production Grid system built on the [[wikipedia:Globus Toolkit|Globus Toolkit]].&amp;lt;ref name=&quot;bazinet2009thesis&quot;&amp;gt;{{Cite &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;thesis &lt;/del&gt;|last=Bazinet |first=Adam L. |title=The Lattice Project: A Multi-model Grid Computing System &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|type=Master&#039;s thesis |publisher=University of Maryland, College Park |year=2009 &lt;/del&gt;|url=https://drum.lib.umd.edu/bitstreams/82bde2fc-1831-47c1-95ad-00ca88268e46/download |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Its best-known use was distributing maximum-likelihood [[wikipedia:phylogenetics|phylogenetic]] analyses through the Genetic Algorithm for Rapid Likelihood Inference (GARLI) program, letting researchers worldwide reconstruct evolutionary relationships from DNA and protein sequence data.&amp;lt;ref name=&quot;wikipedia&quot; /&amp;gt;  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&#039;&#039;&#039;The Lattice Project&#039;&#039;&#039; was a discontinued grid computing and [[wikipedia:volunteer computing|volunteer computing]] system operated by the Laboratory of Molecular Evolution at the [[wikipedia:University of Maryland, College Park|University of Maryland]], College Park.&amp;lt;ref name=&quot;wikipedia&quot;&amp;gt;{{Cite web |title=The Lattice Project |url=https://en.wikipedia.org/wiki/The_Lattice_Project |work=Wikipedia |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Rather than being a single program, Lattice combined several distinct computing resources, including dedicated [[wikipedia:HTCondor|Condor]] pools, [[wikipedia:Portable Batch System|PBS]] compute clusters, and a public [[wikipedia:BOINC|BOINC]] volunteer pool, into one production Grid system built on the [[wikipedia:Globus Toolkit|Globus Toolkit]].&amp;lt;ref name=&quot;bazinet2009thesis&quot;&amp;gt;{{Cite &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;web &lt;/ins&gt;|last=Bazinet |first=Adam L. |title=The Lattice Project: A Multi-model Grid Computing System |url=https://drum.lib.umd.edu/bitstreams/82bde2fc-1831-47c1-95ad-00ca88268e46/download &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|work=Master&#039;s thesis, University of Maryland, College Park |year=2009 &lt;/ins&gt;|access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Its best-known use was distributing maximum-likelihood [[wikipedia:phylogenetics|phylogenetic]] analyses through the Genetic Algorithm for Rapid Likelihood Inference (GARLI) program, letting researchers worldwide reconstruct evolutionary relationships from DNA and protein sequence data.&amp;lt;ref name=&quot;wikipedia&quot; /&amp;gt;  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== History ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== History ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l60&quot;&gt;Line 60:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 60:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Software and applications ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Software and applications ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The flagship application run on the Lattice Grid was GARLI, the Genetic Algorithm for Rapid Likelihood Inference, an open-source phylogenetic inference program written and maintained by Derrick J. Zwickl that searches for the evolutionary tree, branch lengths, and substitution model parameters maximizing the likelihood of a sequence dataset.&amp;lt;ref name=&quot;sysbio2014&quot; /&amp;gt;&amp;lt;ref name=&quot;garliwiki&quot;&amp;gt;{{Cite web |title=Home |url=https://github.com/zwickl/garli/wiki |work=GARLI wiki, GitHub |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; GARLI&#039;s underlying approach was first developed in Zwickl&#039;s 2006 doctoral dissertation at the University of Texas at Austin.&amp;lt;ref name=&quot;zwickl2006&quot;&amp;gt;{{Cite &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;thesis &lt;/del&gt;|last=Zwickl |first=Derrick J. |title=Genetic algorithm approaches for the phylogenetic analysis of large biological sequence datasets under the maximum likelihood criterion |&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;type&lt;/del&gt;=PhD dissertation &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|publisher=&lt;/del&gt;The University of Texas at Austin |year=2006}}&amp;lt;/ref&amp;gt; In general terms, a maximum-likelihood phylogenetic search of this kind seeks the tree topology &amp;lt;math&amp;gt;T&amp;lt;/math&amp;gt;, branch lengths &amp;lt;math&amp;gt;\mathbf{v}&amp;lt;/math&amp;gt;, and model parameters &amp;lt;math&amp;gt;\boldsymbol{\theta}&amp;lt;/math&amp;gt; that maximize&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The flagship application run on the Lattice Grid was GARLI, the Genetic Algorithm for Rapid Likelihood Inference, an open-source phylogenetic inference program written and maintained by Derrick J. Zwickl that searches for the evolutionary tree, branch lengths, and substitution model parameters maximizing the likelihood of a sequence dataset.&amp;lt;ref name=&quot;sysbio2014&quot; /&amp;gt;&amp;lt;ref name=&quot;garliwiki&quot;&amp;gt;{{Cite web |title=Home |url=https://github.com/zwickl/garli/wiki |work=GARLI wiki, GitHub |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; GARLI&#039;s underlying approach was first developed in Zwickl&#039;s 2006 doctoral dissertation at the University of Texas at Austin.&amp;lt;ref name=&quot;zwickl2006&quot;&amp;gt;{{Cite &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;web &lt;/ins&gt;|last=Zwickl |first=Derrick J. |title=Genetic algorithm approaches for the phylogenetic analysis of large biological sequence datasets under the maximum likelihood criterion |&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;url=https://www.bio.utexas.edu/faculty/antisense/garli/Garli.html |work&lt;/ins&gt;=PhD dissertation&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;, &lt;/ins&gt;The University of Texas at Austin |year=2006 &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|access-date=2026-07-14&lt;/ins&gt;}}&amp;lt;/ref&amp;gt; In general terms, a maximum-likelihood phylogenetic search of this kind seeks the tree topology &amp;lt;math&amp;gt;T&amp;lt;/math&amp;gt;, branch lengths &amp;lt;math&amp;gt;\mathbf{v}&amp;lt;/math&amp;gt;, and model parameters &amp;lt;math&amp;gt;\boldsymbol{\theta}&amp;lt;/math&amp;gt; that maximize&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;math&amp;gt;L(T, \mathbf{v}, \boldsymbol{\theta} \mid X) = \prod_{i=1}^{n} P(X_i \mid T, \mathbf{v}, \boldsymbol{\theta})&amp;lt;/math&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;math&amp;gt;L(T, \mathbf{v}, \boldsymbol{\theta} \mid X) = \prod_{i=1}^{n} P(X_i \mid T, \mathbf{v}, \boldsymbol{\theta})&amp;lt;/math&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>Al Piskun</name></author>
	</entry>
	<entry>
		<id>https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1712&amp;oldid=prev</id>
		<title>Al Piskun: add pubs</title>
		<link rel="alternate" type="text/html" href="https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1712&amp;oldid=prev"/>
		<updated>2026-07-14T12:53:02Z</updated>

		<summary type="html">&lt;p&gt;add pubs&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 12:53, 14 July 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l73&quot;&gt;Line 73:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 73:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Analyses run through the Lattice Grid and its GARLI web service contributed to a range of published phylogenetic studies, particularly in the University of Maryland&amp;#039;s own moth and butterfly research program. Examples include a 2009 study on the phylogeny of advanced moths and butterflies (Lepidoptera: Ditrysia), a 2011 study on gene sampling in gracillariid leaf-mining moths, and a 2013 exploratory RNA-Seq study of rapid radiation within Apoditrysia, all of which drew on GARLI analyses of the kind distributed by Lattice.&amp;lt;ref name=&amp;quot;sysbio2014&amp;quot; /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Analyses run through the Lattice Grid and its GARLI web service contributed to a range of published phylogenetic studies, particularly in the University of Maryland&amp;#039;s own moth and butterfly research program. Examples include a 2009 study on the phylogeny of advanced moths and butterflies (Lepidoptera: Ditrysia), a 2011 study on gene sampling in gracillariid leaf-mining moths, and a 2013 exploratory RNA-Seq study of rapid radiation within Apoditrysia, all of which drew on GARLI analyses of the kind distributed by Lattice.&amp;lt;ref name=&amp;quot;sysbio2014&amp;quot; /&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Discontinuation &lt;/del&gt;==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Scientific Publications &lt;/ins&gt;==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Lattice Project is not currently listed among active &lt;/del&gt;BOINC &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;projects&lt;/del&gt;, and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;both &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;its web addresses&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&#039;&#039;lattice&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;umiacs&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;umd&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;edu&#039;&#039; &lt;/del&gt;and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&#039;&#039;boinc&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;umiacs&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;umd&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;edu&#039;&#039;&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;are offline as &lt;/del&gt;of &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;this writing&lt;/del&gt;. &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Because BOINC client software depends on &lt;/del&gt;a &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;project&#039;s own website to retrieve account&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;application&lt;/del&gt;, and &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;scheduling information&lt;/del&gt;, the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;loss &lt;/del&gt;of the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Lattice BOINC website meant volunteer computers could no longer attach to or receive work &lt;/del&gt;from the &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;project&lt;/del&gt;, &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;effectively ending that instance regardless of whether any &lt;/del&gt;Grid &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;infrastructure remained active elsewhere&lt;/del&gt;.&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;ref name=&quot;wikipedia&quot; &lt;/del&gt;/&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Puplications using BOINC-based results as listed on [https://boinc.berkeley.edu/pubs.php#&lt;/ins&gt;The &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Publications by &lt;/ins&gt;BOINC &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Projects] &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Bazinet&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Adam L. &lt;/ins&gt;and &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Michael P. Cummings. [Subdividing Long-Running, Variable-Length Analyses Into Short, Fixed-Length BOINC Workunits](http://link.springer.com/10.1007/s10723-015-9348-5). Journal &lt;/ins&gt;of &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Grid Computing (2016). DOI: 10.1007/s10723-015-9348-5.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Bazinet, Adam L., Derrick J. Zwickl and Michael P. Cummings. [A Gateway for Phylogenetic Analysis Powered by Grid Computing Featuring GARLI 2.0](https://academic.oup.com/sysbio/article/63/5/812/2847779). Systematic Biology (2014). DOI: 10.1093/sysbio/syu031.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Bazinet, Adam L., Michael P. Cummings&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Kim T. Mitter and Charles W. Mitter. [Can RNA-Seq Resolve the Rapid Radiation of Advanced Moths and Butterflies (Hexapoda: Lepidoptera: Apoditrysia)? An Exploratory Study](https://dx.plos.org/10.1371/journal.pone.0082615)&lt;/ins&gt;. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;PLoS ONE (2013)&lt;/ins&gt;. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;DOI: 10&lt;/ins&gt;.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;1371/journal.pone.0082615.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Lloyd, Michael W., Lesley Campbell &lt;/ins&gt;and &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Maile C. Neel. [The Power to Detect Recent Fragmentation Events Using Genetic Differentiation Methods](https://dx.plos.org/10.1371/journal.pone.0063981). PLoS ONE (2013). DOI: 10.1371/journal&lt;/ins&gt;.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;pone&lt;/ins&gt;.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;0063981&lt;/ins&gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Regier&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Jerome C. and Andreas Zwick. [Sources of Signal in 62 Protein-Coding Nuclear Genes for Higher-Level Phylogenetics &lt;/ins&gt;of &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Arthropods](https://dx.plos.org/10.1371/journal.pone.0023408). PLoS ONE (2011). DOI: 10.1371/journal.pone.0023408.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Zwick, Andreas, Jerome C. Regier, Charles Mitter and Michael P. Cummings. [Increased gene sampling yields robust support for higher-level clades within Bombycoidea (Lepidoptera)](https://onlinelibrary.wiley.com/doi/10.1111/j.1365-3113.2010.00543.x). Systematic Entomology (2011). DOI: 10.1111/j.1365-3113.2010.00543.x.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Cho, Soowon, Andreas Zwick, Jerome C. Regier *et al*&lt;/ins&gt;. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[Can Deliberately Incomplete Gene Sample Augmentation Improve &lt;/ins&gt;a &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Phylogeny Estimate for the Advanced Moths and Butterflies (Hexapoda: Lepidoptera)?](https://academic.oup.com/sysbio/article/60/6/782/1678055). Systematic Biology (2011). DOI: 10.1093/sysbio/syr079.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Kawahara, Akito Y, Issei Ohshima, Atsushi Kawakita *et al*. [Increased gene sampling strengthens support for higher-level groups within leaf-mining moths and relatives (Lepidoptera: Gracillariidae)](http://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2148-11-182). BMC Evolutionary Biology (2011). DOI: 10.1186/1471-2148-11-182.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Reyna-Fabián, Miriam E.&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Juan Pedro Laclette&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Michael P. Cummings &lt;/ins&gt;and &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Martín García-Varela. [Validating the systematic position of Plationus Segers&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Murugan &amp;amp; Dumont, 1993 (Rotifera: Brachionidae) using sequences of &lt;/ins&gt;the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;large subunit &lt;/ins&gt;of the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;nuclear ribosomal DNA and of cytochrome C oxidase](http://link.springer.com/10.1007/s10750-010-0203-1). Hydrobiologia (2010). DOI: 10.1007/s10750-010-0203-1.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Regier, Jerome C., Jeffrey W. Shultz, Andreas Zwick, April Hussey, Bernard Ball, Regina Wetzer, Joel W. Martin and Clifford W. Cunningham. [Arthropod relationships revealed by phylogenomic analysis of nuclear protein-coding sequences](http://www.nature.com/articles/nature08742). Nature (2010). DOI: 10.1038/nature08742.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Regier, Jerome C, Andreas Zwick, Michael P Cummings *et al*. [Toward reconstructing the evolution of advanced moths and butterflies (Lepidoptera: Ditrysia): an initial molecular study](https://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2148-9-280). BMC Evolutionary Biology (2009). DOI: 10.1186/1471-2148-9-280.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Pettengill, James B and Maile C Neel. [Phylogenetic patterns and conservation among North American members of the genus Agalinis (Orobanchaceae)](http://bmcevolbiol.biomedcentral.com/articles/10.1186/1471-2148-8-264). BMC Evolutionary Biology (2008). DOI: 10.1186/1471-2148-8-264.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Bazinet, Adam L., Daniel S. Myers, John Fuetsch and Michael P. Cummings. [Grid Services Base Library: A high-level, procedural application programming interface for writing Globus-based Grid services](https://linkinghub.elsevier.com/retrieve/pii/S0167739X06001464). Future Generation Computer Systems (2007). DOI: 10.1016/j.future.2006.07.009.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Tishkoff, S. A., M. K. Gonder, B. M. Henn *et al*. [History of Click-Speaking Populations of Africa Inferred &lt;/ins&gt;from &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;mtDNA and Y Chromosome Genetic Variation](https://academic.oup.com/mbe/article-lookup/doi/10.1093/molbev/msm155). Molecular Biology and Evolution (2007). DOI: 10.1093/molbev/msm155.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Myers, Daniel S., Adam L. Bazinet and Michael P. Cummings. [Expanding &lt;/ins&gt;the &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Reach of Grid Computing: Combining Globus- and BOINC-Based Systems](https://onlinelibrary.wiley.com/doi/10.1002/9780470191637.ch4). Grid Computing for Bioinformatics and Computational Biology (2007).&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;# Lee, Sung&lt;/ins&gt;, &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Taowei David Wang, Nada Hashmi and Michael P. Cummings. [Bio-STEER: A Semantic Web workflow tool for &lt;/ins&gt;Grid &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;computing in the life sciences](https://linkinghub&lt;/ins&gt;.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;elsevier.com/retrieve/pii/S0167739X06001439). Future Generation Computer Systems (2007). DOI: 10.1016&lt;/ins&gt;/&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;j.future.2006.07.011.&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== See also ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== See also ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>Al Piskun</name></author>
	</entry>
	<entry>
		<id>https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1711&amp;oldid=prev</id>
		<title>Al Piskun at 12:23, 14 July 2026</title>
		<link rel="alternate" type="text/html" href="https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1711&amp;oldid=prev"/>
		<updated>2026-07-14T12:23:24Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 12:23, 14 July 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l37&quot;&gt;Line 37:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 37:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[File:University of Maryland (5354729497).jpg|thumb|The Lattice Project was developed and administered at the [[wikipedia:University of Maryland, College Park|University of Maryland, College Park]].]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[File:University of Maryland (5354729497).jpg|thumb|The Lattice Project was developed and administered at the [[wikipedia:University of Maryland, College Park|University of Maryland, College Park]].]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&#039;&#039;&#039;The Lattice Project&#039;&#039;&#039; was a discontinued grid computing and [[wikipedia:volunteer computing|volunteer computing]] system operated by the Laboratory of Molecular Evolution at the [[wikipedia:University of Maryland, College Park|University of Maryland]], College Park.&amp;lt;ref name=&quot;wikipedia&quot;&amp;gt;{{Cite web |title=The Lattice Project |url=https://en.wikipedia.org/wiki/The_Lattice_Project |work=Wikipedia |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Rather than being a single program, Lattice combined several distinct computing resources, including dedicated [[wikipedia:HTCondor|Condor]] pools, [[wikipedia:Portable Batch System|PBS]] compute clusters, and a public [[wikipedia:BOINC|BOINC]] volunteer pool, into one production Grid system built on the [[wikipedia:Globus Toolkit|Globus Toolkit]].&amp;lt;ref name=&quot;bazinet2009thesis&quot;&amp;gt;{{Cite thesis |last=Bazinet |first=Adam L. |title=The Lattice Project: A Multi-model Grid Computing System |type=Master&#039;s thesis |publisher=University of Maryland, College Park |year=2009 |url=https://drum.lib.umd.edu/bitstreams/82bde2fc-1831-47c1-95ad-00ca88268e46/download |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Its best-known use was distributing maximum-likelihood [[wikipedia:phylogenetics|phylogenetic]] analyses through the Genetic Algorithm for Rapid Likelihood Inference (GARLI) program, letting researchers worldwide reconstruct evolutionary relationships from DNA and protein sequence data.&amp;lt;ref name=&quot;wikipedia&quot; /&amp;gt; &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Because the project offered two distinct, separately administered instances, &quot;the Lattice Grid&quot; and &quot;the Lattice BOINC Project&quot;, it is described here in both of its forms below.&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&#039;&#039;&#039;The Lattice Project&#039;&#039;&#039; was a discontinued grid computing and [[wikipedia:volunteer computing|volunteer computing]] system operated by the Laboratory of Molecular Evolution at the [[wikipedia:University of Maryland, College Park|University of Maryland]], College Park.&amp;lt;ref name=&quot;wikipedia&quot;&amp;gt;{{Cite web |title=The Lattice Project |url=https://en.wikipedia.org/wiki/The_Lattice_Project |work=Wikipedia |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Rather than being a single program, Lattice combined several distinct computing resources, including dedicated [[wikipedia:HTCondor|Condor]] pools, [[wikipedia:Portable Batch System|PBS]] compute clusters, and a public [[wikipedia:BOINC|BOINC]] volunteer pool, into one production Grid system built on the [[wikipedia:Globus Toolkit|Globus Toolkit]].&amp;lt;ref name=&quot;bazinet2009thesis&quot;&amp;gt;{{Cite thesis |last=Bazinet |first=Adam L. |title=The Lattice Project: A Multi-model Grid Computing System |type=Master&#039;s thesis |publisher=University of Maryland, College Park |year=2009 |url=https://drum.lib.umd.edu/bitstreams/82bde2fc-1831-47c1-95ad-00ca88268e46/download |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Its best-known use was distributing maximum-likelihood [[wikipedia:phylogenetics|phylogenetic]] analyses through the Genetic Algorithm for Rapid Likelihood Inference (GARLI) program, letting researchers worldwide reconstruct evolutionary relationships from DNA and protein sequence data.&amp;lt;ref name=&quot;wikipedia&quot; /&amp;gt;  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== History ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== History ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Al Piskun</name></author>
	</entry>
	<entry>
		<id>https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1710&amp;oldid=prev</id>
		<title>Al Piskun: first light</title>
		<link rel="alternate" type="text/html" href="https://boincsynergy.ca/wiki/index.php?title=The_Lattice_Project&amp;diff=1710&amp;oldid=prev"/>
		<updated>2026-07-14T12:22:46Z</updated>

		<summary type="html">&lt;p&gt;first light&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;{{Infobox software&lt;br /&gt;
| name                 = The Lattice Project&lt;br /&gt;
| logo                 = Lattice-project.gif&lt;br /&gt;
| logo caption         = &lt;br /&gt;
| screenshot           = &lt;br /&gt;
| caption              = &lt;br /&gt;
| description          = The Lattice Project was a discontinued grid and volunteer computing initiative from the University of Maryland that combined a BOINC-based public computing pool with Condor and PBS clusters through the Globus Toolkit, chiefly supporting phylogenetic analysis with the GARLI software.&lt;br /&gt;
| status               = Completed&lt;br /&gt;
| category             = Bioinformatics, Computational biology, Phylogenetics&lt;br /&gt;
| compute              = CPU&lt;br /&gt;
| dependencies         = &lt;br /&gt;
| developer            = Adam L. Bazinet&lt;br /&gt;
| author               = Michael P. Cummings (principal investigator); Adam L. Bazinet (lead developer)&lt;br /&gt;
| sponsor              = University of Maryland Institute for Advanced Computer Studies (UMIACS); Center for Bioinformatics and Computational Biology, University of Maryland&lt;br /&gt;
| maintainer           = None (discontinued)&lt;br /&gt;
| released             = {{Start date and age|2007|12|18}}&lt;br /&gt;
| completed            = {{Start date and age|2017|05|17}} (exact date unrecorded)&lt;br /&gt;
| discontinued         = &lt;br /&gt;
| repository           = &lt;br /&gt;
| programming language = Java (Grid middleware); C++ (scientific applications such as GARLI)&lt;br /&gt;
| operating system     = Windows, Linux, macOS&lt;br /&gt;
| size                 = &lt;br /&gt;
| stats as of          = {{Start date and age|2014|6|16}}&lt;br /&gt;
| average performance  = &lt;br /&gt;
| active users         = &lt;br /&gt;
| total users          = 17,000+&lt;br /&gt;
| active hosts         = &lt;br /&gt;
| total hosts          = 38,740&lt;br /&gt;
| rac                  = &lt;br /&gt;
| credit per day       = &lt;br /&gt;
| gpu performance      = &lt;br /&gt;
| cpu performance      = &lt;br /&gt;
| website              = {{URL|http://lattice.umiacs.umd.edu/}} and 2nd URL - {{URL|http://boinc.umiacs.umd.edu/}}&lt;br /&gt;
| license              = Not uniformly licensed; some constituent applications (e.g. GARLI) distributed as open source&lt;br /&gt;
}}&lt;br /&gt;
&lt;br /&gt;
[[File:University of Maryland (5354729497).jpg|thumb|The Lattice Project was developed and administered at the [[wikipedia:University of Maryland, College Park|University of Maryland, College Park]].]]&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;The Lattice Project&amp;#039;&amp;#039;&amp;#039; was a discontinued grid computing and [[wikipedia:volunteer computing|volunteer computing]] system operated by the Laboratory of Molecular Evolution at the [[wikipedia:University of Maryland, College Park|University of Maryland]], College Park.&amp;lt;ref name=&amp;quot;wikipedia&amp;quot;&amp;gt;{{Cite web |title=The Lattice Project |url=https://en.wikipedia.org/wiki/The_Lattice_Project |work=Wikipedia |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Rather than being a single program, Lattice combined several distinct computing resources, including dedicated [[wikipedia:HTCondor|Condor]] pools, [[wikipedia:Portable Batch System|PBS]] compute clusters, and a public [[wikipedia:BOINC|BOINC]] volunteer pool, into one production Grid system built on the [[wikipedia:Globus Toolkit|Globus Toolkit]].&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot;&amp;gt;{{Cite thesis |last=Bazinet |first=Adam L. |title=The Lattice Project: A Multi-model Grid Computing System |type=Master&amp;#039;s thesis |publisher=University of Maryland, College Park |year=2009 |url=https://drum.lib.umd.edu/bitstreams/82bde2fc-1831-47c1-95ad-00ca88268e46/download |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Its best-known use was distributing maximum-likelihood [[wikipedia:phylogenetics|phylogenetic]] analyses through the Genetic Algorithm for Rapid Likelihood Inference (GARLI) program, letting researchers worldwide reconstruct evolutionary relationships from DNA and protein sequence data.&amp;lt;ref name=&amp;quot;wikipedia&amp;quot; /&amp;gt; Because the project offered two distinct, separately administered instances, &amp;quot;the Lattice Grid&amp;quot; and &amp;quot;the Lattice BOINC Project&amp;quot;, it is described here in both of its forms below.&lt;br /&gt;
&lt;br /&gt;
== History ==&lt;br /&gt;
The system that became the Lattice Project grew out of earlier commodity Grid computing experiments at Maryland&amp;#039;s Center for Bioinformatics and Computational Biology, first described by David Myers and Michael Cummings in a 2003 paper on combining Condor pools with simple job-submission tools.&amp;lt;ref name=&amp;quot;myers2003&amp;quot;&amp;gt;{{Cite journal |last1=Myers |first1=David S. |last2=Cummings |first2=Michael P. |title=Necessity is the mother of invention: a simple grid computing system using commodity tools |journal=Journal of Parallel and Distributed Computing |volume=63 |issue=5 |pages=578-589 |year=2003}}&amp;lt;/ref&amp;gt; That work developed into a full production Grid, described publicly by Cummings in 2005 and formally written up by Bazinet and Cummings in a 2008 book chapter on combining multiple Grid computing models.&amp;lt;ref name=&amp;quot;bazinet2008chapter&amp;quot;&amp;gt;{{Cite book |last1=Bazinet |first1=Adam L. |last2=Cummings |first2=Michael P. |title=Distributed &amp;amp; Grid Computing: Science Made Transparent for Everyone. Principles, Applications and Supporting Communities |chapter=The Lattice Project: a Grid research and production environment combining multiple Grid computing models |editor-last=Weber |editor-first=Marc H. W. |publisher=Rechenkraft.net |location=Marburg |pages=2-13 |year=2008}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The volunteer-facing BOINC instance was formally opened to the public in a BOINC News announcement by project developer David Anderson, who described Lattice as supplying computing power for research into evolutionary relationships from DNA sequence data, bacterial and viral protein sequences, and biological diversity in nature reserves.&amp;lt;ref name=&amp;quot;anderson2007&amp;quot;&amp;gt;{{Cite web |last=Anderson |first=David |title=The Lattice Project, based at the University of Maryland Center for Bioinformatics and Computational Biology, is now open to volunteers |url=https://boinc.berkeley.edu/forum_thread.php?id=5208 |work=BOINC |date=2007-12-18 |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; Bazinet&amp;#039;s 2009 master&amp;#039;s thesis subsequently documented the combined architecture in detail, describing a base of four Condor pools, three PBS clusters, and one BOINC pool at that time.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
In 2010, researchers at Maryland and the University of Arizona layered a public web gateway, &amp;#039;&amp;#039;molecularevolution.org&amp;#039;&amp;#039;, on top of the Grid, giving anyone with a browser access to Lattice&amp;#039;s phylogenetic computing power rather than requiring the BOINC client.&amp;lt;ref name=&amp;quot;genomeweb&amp;quot;&amp;gt;{{Cite web |title=UMD-developed Infrastructure Offers Hardware, Software for Phylogenetic Analysis |url=https://www.genomeweb.com/informatics/umd-developed-infrastructure-offers-hardware-software-phylogenetic-analysis |work=GenomeWeb |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; By 2014, the university reported that more than 17,000 volunteers from 146 countries had contributed computing time to the project, with 38,740 personal computers registered to the BOINC pool alongside institutional resources at UMIACS, Coppin State University, and the Smithsonian Institution.&amp;lt;ref name=&amp;quot;umd2014&amp;quot;&amp;gt;{{Cite web |last=Cummings |first=Michael |title=UMD-led Public Computational Biology Web Service Gains Popularity |url=https://cmns.umd.edu/news-events/news/umd-led-public-computational-biology-web-service-gains-popularity |work=University of Maryland College of Computer, Mathematical, and Natural Sciences |date=2014-06-16 |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; That same year Bazinet, Zwickl, and Cummings formally described the GARLI 2.0 web service built atop the Grid,&amp;lt;ref name=&amp;quot;sysbio2014&amp;quot;&amp;gt;{{Cite journal |last1=Bazinet |first1=Adam L. |last2=Zwickl |first2=Derrick J. |last3=Cummings |first3=Michael P. |title=A Gateway for Phylogenetic Analysis Powered by Grid Computing Featuring GARLI 2.0 |journal=Systematic Biology |volume=63 |issue=5 |pages=812-818 |year=2014 |doi=10.1093/sysbio/syu031}}&amp;lt;/ref&amp;gt; and in 2015 Bazinet and Cummings published a follow-up study on subdividing long BOINC workunits to improve throughput on the Lattice BOINC Project specifically.&amp;lt;ref name=&amp;quot;jgc2015&amp;quot;&amp;gt;{{Cite journal |last1=Bazinet |first1=Adam L. |last2=Cummings |first2=Michael P. |title=Subdividing Long-Running, Variable-Length Analyses Into Short, Fixed-Length BOINC Workunits |journal=Journal of Grid Computing |year=2015 |doi=10.1007/s10723-015-9348-5}}&amp;lt;/ref&amp;gt; A March 2015 forum thread on BOINCstats/BAM! confirms that the project&amp;#039;s servers were still reporting recent throughput at that time.&amp;lt;ref name=&amp;quot;boincstats2015&amp;quot;&amp;gt;{{Cite web |title=Forum::New projects::Lattice |url=https://www.boincstats.com/forum/11/9907,1 |work=BOINCstats/BAM! |access-date=2026-07-14}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
The project was eventually discontinued. According to the English Wikipedia&amp;#039;s account, the Lattice BOINC website went offline, and because BOINC clients depend on a project&amp;#039;s website to retrieve setup and scheduling information, the loss of that site effectively shut the volunteer computing instance down.&amp;lt;ref name=&amp;quot;wikipedia&amp;quot; /&amp;gt; The exact discontinuation date was not documented in any source found for this article, but the site was already inactive by the time the Wikipedia article&amp;#039;s supporting citation was archived in September 2017.&amp;lt;ref name=&amp;quot;wikipedia&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== The Lattice Grid ==&lt;br /&gt;
[[File:Condor logo.png|thumb|The Lattice Grid combined dedicated [[wikipedia:HTCondor|Condor]] pools with PBS clusters and the BOINC volunteer pool under a single Globus-based scheduling layer.]]&lt;br /&gt;
The Lattice Grid, reachable at &amp;#039;&amp;#039;lattice.umiacs.umd.edu&amp;#039;&amp;#039;, was the research and production Grid environment underlying the whole project. It ran the full [[wikipedia:Globus Toolkit|Globus Toolkit]] software stack, including a web services container for deploying Grid-enabled applications, and used the Grid Security Infrastructure for authentication and authorization across participating resources.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt; At the time of Bazinet&amp;#039;s 2009 thesis, the Grid drew on roughly 4,000 to 5,000 CPUs contributed by groups within the University of Maryland (UMIACS, the Office of Information Technology, and other campus units) as well as external partners such as Coppin State University.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Rather than replacing existing campus computing infrastructure, the Lattice Grid was designed to federate it: local resources running [[wikipedia:HTCondor|Condor]] or [[wikipedia:Portable Batch System|PBS]] could be tied into the Grid by installing Globus on a submission node, after which jobs could be routed to whichever available resource, dedicated cluster, Condor pool, or the BOINC volunteer pool, suited the workload.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt; The Grid server itself handled transitory job storage and coordinated data transfer over GridFTP, while a separate &amp;quot;sister&amp;quot; server, contemporaneously described as running with 8 GB of RAM, was dedicated specifically to powering the BOINC-facing project.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== The Lattice BOINC Project ==&lt;br /&gt;
The Lattice BOINC Project, at &amp;#039;&amp;#039;boinc.umiacs.umd.edu&amp;#039;&amp;#039;, was the public-facing volunteer computing instance of the Grid and the piece most familiar to ordinary [[wikipedia:BOINC|BOINC]] users. It was announced to the wider BOINC community in December 2007 as being open to volunteers, supplying computing power to researchers studying evolutionary relationships from DNA sequence data, protein sequence comparison, and even conservation reserve network design.&amp;lt;ref name=&amp;quot;anderson2007&amp;quot; /&amp;gt; Community-maintained BOINC project listings describe it as running on Macintosh, Linux, and Windows, without GPU acceleration and without an OpenGL screensaver, distinguishing it from many contemporaneous BOINC projects that had already added GPU support.&amp;lt;ref name=&amp;quot;mundayweb&amp;quot;&amp;gt;{{Cite web |title=The Lattice Project |url=https://boinc.mundayweb.com/wiki/index.php?title=The_Lattice_Project |work=BOINC Wiki (Mundayweb) |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; The project was also listed among the participating projects on the volunteer computing aggregator GridRepublic, which summarized it simply as supporting the work of researchers at the University of Maryland.&amp;lt;ref name=&amp;quot;gridrepublic&amp;quot;&amp;gt;{{Cite web |title=GridRepublic: About |url=http://www.gridrepublic.org/index.php?page=about&amp;amp;id=3 |work=GridRepublic |access-date=2026-07-14}}&amp;lt;/ref&amp;gt;&lt;br /&gt;
&lt;br /&gt;
Unlike many single-application BOINC projects, the Lattice BOINC Project was designed from the outset to serve multiple scientific applications rather than one; David Anderson&amp;#039;s original announcement noted that volunteers might receive workunits from a variety of different research applications rather than a single program, a design choice acknowledged in the project&amp;#039;s own documentation as something of a public-relations challenge, since users could not always predict what kind of task their computer would be asked to run.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== Software and applications ==&lt;br /&gt;
The flagship application run on the Lattice Grid was GARLI, the Genetic Algorithm for Rapid Likelihood Inference, an open-source phylogenetic inference program written and maintained by Derrick J. Zwickl that searches for the evolutionary tree, branch lengths, and substitution model parameters maximizing the likelihood of a sequence dataset.&amp;lt;ref name=&amp;quot;sysbio2014&amp;quot; /&amp;gt;&amp;lt;ref name=&amp;quot;garliwiki&amp;quot;&amp;gt;{{Cite web |title=Home |url=https://github.com/zwickl/garli/wiki |work=GARLI wiki, GitHub |access-date=2026-07-14}}&amp;lt;/ref&amp;gt; GARLI&amp;#039;s underlying approach was first developed in Zwickl&amp;#039;s 2006 doctoral dissertation at the University of Texas at Austin.&amp;lt;ref name=&amp;quot;zwickl2006&amp;quot;&amp;gt;{{Cite thesis |last=Zwickl |first=Derrick J. |title=Genetic algorithm approaches for the phylogenetic analysis of large biological sequence datasets under the maximum likelihood criterion |type=PhD dissertation |publisher=The University of Texas at Austin |year=2006}}&amp;lt;/ref&amp;gt; In general terms, a maximum-likelihood phylogenetic search of this kind seeks the tree topology &amp;lt;math&amp;gt;T&amp;lt;/math&amp;gt;, branch lengths &amp;lt;math&amp;gt;\mathbf{v}&amp;lt;/math&amp;gt;, and model parameters &amp;lt;math&amp;gt;\boldsymbol{\theta}&amp;lt;/math&amp;gt; that maximize&lt;br /&gt;
&lt;br /&gt;
&amp;lt;math&amp;gt;L(T, \mathbf{v}, \boldsymbol{\theta} \mid X) = \prod_{i=1}^{n} P(X_i \mid T, \mathbf{v}, \boldsymbol{\theta})&amp;lt;/math&amp;gt;&lt;br /&gt;
&lt;br /&gt;
over the columns &amp;lt;math&amp;gt;X_i&amp;lt;/math&amp;gt; of a sequence alignment &amp;lt;math&amp;gt;X&amp;lt;/math&amp;gt;, a computation that becomes extremely demanding as the number of taxa grows, which is precisely the kind of workload the Lattice Grid was built to distribute across thousands of processors.&amp;lt;ref name=&amp;quot;sysbio2014&amp;quot; /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[File:Metazoan Phylogenetic Tree.png|thumb|An example of a maximum-likelihood phylogenetic tree of the general kind produced by GARLI analyses distributed across the Lattice Grid.]]&lt;br /&gt;
&lt;br /&gt;
Beyond GARLI, Bazinet&amp;#039;s 2009 thesis documents other Grid-enabled applications run on Lattice, including HMMPfam for protein sequence comparison and MARXAN for conservation reserve network design, alongside a number of older research applications from the project&amp;#039;s earlier years.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt; By the project&amp;#039;s own account, roughly 25 applications had been Grid-enabled over its lifetime, though only a subset saw significant production use.&amp;lt;ref name=&amp;quot;bazinet2009thesis&amp;quot; /&amp;gt;&lt;br /&gt;
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== Research output ==&lt;br /&gt;
Analyses run through the Lattice Grid and its GARLI web service contributed to a range of published phylogenetic studies, particularly in the University of Maryland&amp;#039;s own moth and butterfly research program. Examples include a 2009 study on the phylogeny of advanced moths and butterflies (Lepidoptera: Ditrysia), a 2011 study on gene sampling in gracillariid leaf-mining moths, and a 2013 exploratory RNA-Seq study of rapid radiation within Apoditrysia, all of which drew on GARLI analyses of the kind distributed by Lattice.&amp;lt;ref name=&amp;quot;sysbio2014&amp;quot; /&amp;gt;&lt;br /&gt;
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== Discontinuation ==&lt;br /&gt;
The Lattice Project is not currently listed among active BOINC projects, and both of its web addresses, &amp;#039;&amp;#039;lattice.umiacs.umd.edu&amp;#039;&amp;#039; and &amp;#039;&amp;#039;boinc.umiacs.umd.edu&amp;#039;&amp;#039;, are offline as of this writing. Because BOINC client software depends on a project&amp;#039;s own website to retrieve account, application, and scheduling information, the loss of the Lattice BOINC website meant volunteer computers could no longer attach to or receive work from the project, effectively ending that instance regardless of whether any Grid infrastructure remained active elsewhere.&amp;lt;ref name=&amp;quot;wikipedia&amp;quot; /&amp;gt;&lt;br /&gt;
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== See also ==&lt;br /&gt;
* [[SETI@home]]&lt;br /&gt;
* [[World Community Grid]]&lt;br /&gt;
* [[Docking@Home]]&lt;br /&gt;
* [[wikipedia:BOINC|BOINC]]&lt;br /&gt;
* [[wikipedia:Grid computing|Grid computing]]&lt;br /&gt;
* [[wikipedia:GARLI|GARLI]]&lt;br /&gt;
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== References ==&lt;br /&gt;
{{Reflist}}&lt;/div&gt;</summary>
		<author><name>Al Piskun</name></author>
	</entry>
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