Proteins@home: Difference between revisions

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'''Proteins@home''' (styled ''proteins@home'') was a non-profit [[volunteer computing]] project built on the [[Berkeley Open Infrastructure for Network Computing]] (BOINC) platform.<ref name="wikipedia">{{cite encyclopedia |title=Proteins@home |encyclopedia=Wikipedia |url=https://en.wikipedia.org/wiki/Proteins@home |access-date=2026-06-08}}</ref> The project ran from December 28, 2006 to June 2008 and was operated by the Laboratoire de Biochimie (CNRS UMR&nbsp;7654) in the Department of Biology at [[École Polytechnique]], located in Palaiseau, near Paris, France.<ref name="boinc-news">{{cite web |url=https://boinc.berkeley.edu/forum_thread.php?id=5136 |title=The Proteins@Home project is now open |publisher=BOINC Message Boards |date=2006-12-28 |access-date=2026-06-08}}</ref> Its scientific goal was to map the ''inverse protein folding problem'' across approximately 1,500 representative [[protein fold|protein folds]], building a database of pairwise energy functions that could be used to predict protein structure, understand protein evolution, and design new proteins with potential biomedical applications.<ref name="projdescription">{{cite web |url=https://web.archive.org/web/20070601000000*/http://biology.polytechnique.fr/proteinsathome/ |title=proteins@home |publisher=Wayback Machine |access-date=2026-06-08}}</ref>
'''[https://web.archive.org/web/20070306022756/http://biology.polytechnique.fr/proteinsathome/ Proteins@home]''' (styled ''proteins@home'') was a non-profit [[volunteer computing]] project built on the [[Berkeley Open Infrastructure for Network Computing]] (BOINC) platform.<ref name="wikipedia">{{cite encyclopedia |title=Proteins@home |encyclopedia=Wikipedia |url=https://en.wikipedia.org/wiki/Proteins@home |access-date=2026-06-08}}</ref> The project ran from December 28, 2006 to June 2008 and was operated by the Laboratoire de Biochimie (CNRS UMR&nbsp;7654) in the Department of Biology at [[École Polytechnique]], located in Palaiseau, near Paris, France.<ref name="boinc-news">{{cite web |url=https://boinc.berkeley.edu/forum_thread.php?id=5136 |title=The Proteins@Home project is now open |publisher=BOINC Message Boards |date=2006-12-28 |access-date=2026-06-08}}</ref> Its scientific goal was to map the ''inverse protein folding problem'' across approximately 1,500 representative [[protein fold|protein folds]], building a database of pairwise energy functions that could be used to predict protein structure, understand protein evolution, and design new proteins with potential biomedical applications.<ref name="projdescription">{{cite web |url=https://web.archive.org/web/20070601000000*/http://biology.polytechnique.fr/proteinsathome/ |title=proteins@home |publisher=Wayback Machine |access-date=2026-06-08}}</ref>


== Background ==
== Background ==
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* [https://web.archive.org/web/20080101000000*/http://biology.polytechnique.fr/proteinsathome/ Proteins@home official website (Wayback Machine)]
* [https://web.archive.org/web/20080101000000*/http://biology.polytechnique.fr/proteinsathome/ Proteins@home official website (Wayback Machine)]
* [https://boinc.berkeley.edu/wiki/Proteins@Home Proteins@Home] at the BOINC wiki
* [https://proteus.polytechnique.fr/ Proteus] — successor software package, École Polytechnique
* [https://proteus.polytechnique.fr/ Proteus] — successor software package, École Polytechnique
* [https://commons.wikimedia.org/wiki/Category:Proteins@home Proteins@home] at Wikimedia Commons
* [https://commons.wikimedia.org/wiki/Category:Proteins@home Proteins@home] at Wikimedia Commons