...nergy functions in support of computational protein design and the inverse protein folding problem.
...' computers to help solve the ''inverse protein folding problem'': given a protein's three-dimensional fold, which amino acid sequences are compatible with th
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12 KB (1,599 words) - 14:10, 5 July 2026
| screenshot = Protein structure (1).png
| caption = Protein structure prediction, the kind of computation TreeThreader performed on CAS@home
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13 KB (1,790 words) - 18:18, 3 July 2026
...y = [[wikipedia:Protein structure prediction|Protein structure prediction]], [[wikipedia:Bioinformatics|bioinformatics]], [[wikipedia:Molecular biolo
...ein folding|protein folding]], protein structure prediction, computational protein design, drug discovery, vaccine development, and molecular modeling.<ref>{{
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11 KB (1,445 words) - 18:27, 7 June 2026
...project, run by The Scripps Research Institute to predict protein tertiary structure from amino acid sequences, active from 2004 to 2009.
...rstens, A., Brooks III, C.L. (2005). "Predictor@Home: A 'Protein Structure Prediction Supercomputer' Based on Global Computing". ''IEEE Transactions on Parallel
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18 KB (2,374 words) - 13:45, 3 June 2026
| caption = Rosetta@home screensaver showing protein folding simulations
| category = Bioinformatics, Protein structure prediction, Distributed computing
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17 KB (2,106 words) - 13:37, 29 May 2026
...Tokyo University of Science that used a Brownian dynamics method to study protein folding, operating from 2006 until a fatal server failure in 2008.
...Its name comes from the Japanese word ''tanpaku-shitsu'' ( 蛋白質 ), meaning "protein".<ref name="boincnews">{{Cite web |title=The TANPAKU project, based at the
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12 KB (1,649 words) - 19:35, 12 July 2026
...l-time animated screensaver showing the computation in progress, including protein chains folding, star fields sweeping and climate models spinning. All 71 kn
| * [[MilkyWay@home]] mapping the Milky Way's structure
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17 KB (1,720 words) - 13:01, 14 July 2026
...n: radio telescope signals sweeping across a star field for [[SETI@home]], protein chains folding in three dimensions for [[Rosetta@home]], or a climate model
...lign:top; padding:6px;" | '''[[Rosetta@home]]'''<br/><small>Biochemistry / Protein folding</small>
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33 KB (4,867 words) - 17:01, 3 July 2026
...BOINC project hosted by the University of Delaware that used CHARMM-based protein-ligand docking simulations to search for new pharmaceutical drugs, develope
...[[wikipedia:Ligand (biochemistry)|ligand]]) binds to a [[wikipedia:Protein|protein]] target. The project was created by computer scientist and computational b
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25 KB (3,276 words) - 00:17, 26 June 2026
...ples is the ribosome, a complex ribonucleoprotein assembly responsible for protein synthesis. The catalytic core of the ribosome is itself composed primarily
|title=Revolutions in RNA secondary structure prediction
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12 KB (1,594 words) - 13:08, 29 May 2026
| [https://www.cpdn.org/cpdnboinc/ climate''prediction''.net]
| [https://podcasts.apple.com/us/podcast/climate-prediction-dot-net/id1492837872?i=1000465982378 Listen]
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94 KB (12,485 words) - 23:08, 14 July 2026
...worldwide to donate idle computing cycles to help calculate the electronic structure and [[molecular geometry]] of small molecules.<ref name="wikipedia">{{cite
...articularly valuable in demonstrating that stochastic many-body electronic structure calculations — which require enormous numbers of independent samples — are
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17 KB (2,292 words) - 16:44, 13 June 2026
...'', in which candidate drug molecules are algorithmically fitted to target protein structures to predict binding affinity. A typical project may dock tens of
...1 & 2) || Protein structure prediction || Produced a database of ~120,000 protein domain structures; computation that would have taken 100 years conventional
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86 KB (11,993 words) - 18:40, 8 July 2026